Item RM/4/3/4 - Correspondence with Charles Upton Lowe

Extent: 1 folder

Correspondence between RM and Charles Upton Lowe, State University of New York at Buffalo, USA. Lowe spent 20 months training at the VRU under Roy Markham (1960-61) working on nucleic acid metabolism. Includes detailed reports on his work at the VRU and bibliography. Lowe started work on identifying compounds produced by heating ammonium crystals in aqueous solutions with unexpectedly interesting results, identifying a large number of important biological molecules. RM and his wife later stayed with the Lowe family while visiting the US. Includes letters between RM and Leon A Heppel regarding extending Lowe's grant to stay longer.

Admin History: Charles Upton Lowe (24 Aug 1921-9 Feb 2012) graduated from Harvard 1942 and Yale Med. Sch. 1945, worked in pediatrics at Massachusetts General Hospital where he discovered a sex-linked metobolic disorder known as Lowe Syndrome OCRL (oculo-cerebro-renal) syndrome. He was made Professor of Medicine and a Buswell Fellow at University of Buffalo, NY in 1951. He spent a two-year sabbatical at the Virus Research Laboratory (1960-1961). From 1965-1968, he was Professor of Pediatrics and Director of the Human Development Center at the University of Florida, Gainesville. While there he completed a national survey of nutrition among pre-school children and conducted studies on the modification of human metabolism in metabolic diseases. In 1968 he became the Scientific Director of the National Institute of Child Health and Human Development, NIH, Bethesda, MD.