Item DH/6/3/2 - Papers with Chaitan Khosla/Polyketides

Extent: 1 folder

Reprints, correspondence and research notes re papers on Polyketides with Chaitan Khosla and others: 'Engineered Biosynthesis of Novel Polyketides', Robert McDaniel, Susanne Ebert-Khosla, David A Hopwood and Chaitan Khosla' (1993); 'Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin', Maureen J Bibb, David H Sherman, Satoshi Omura and David A Hopwood (1994); 'Engineered Biosynthesis of Novel Polyketides: Dissection of Catalytic Specificity of the act Ketoreductase', Hong Fu, Susanne Ebert-Khosla, David A Hopwood and Chaitan Khosla (1994); 'Engineered Biosynthesis of Novel Polyketides: Stereochemical Course of Two reactions Catalyzed by a Polyketide Synthase', Hong Fu, Robert McDaniel, David A Hopwood and Chaitan Khosla (1994); 'Relaxed Specificity of the Oxytetracycline Polyketide Synthase for an Acetate Primer in the Absence of a Malonamyl Primer', Hong Fu, Susanne Ebert-Khosla, David A Hopwood and Chaitan Khosla (1994); 'Engineered Biosynthesis of Novel Polyketides: actVII and actIV Genes Encode Aromatase and Cyclase Enzymes, Respectively', Robert McDaniel, Susanne Ebert-Khosla, David A Hopwood and Chaitan Khosla (1994); 'Engineered Biosynthesis of Novel Polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor', Hong Fu, David A Hopwood and Chaitan Khosla (1994); 'Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits', Robert McDaniel, Susanne Ebert-Khosla, David A Hopwood and Chaitan Khosla (1995); 'Expression of a Functional Fungal Polyketide Synthase in the Bacterium Streptomyces coelicolor A3(2)', David J Bedford, Eckhart Schweizer, david A Hopwood and Chaitan Khosla (1995); 'Engineered Biosynthesis of novel Polykeptides: Properties of the whiE Aromatase/Cyclase', Miguel A Alvarez, Hong Fu, Chaitan Khosla, David A Hopwood and James E Bailey (1995); 'Rational Design and Engineered Biosynthesis of a Novel 18-Carbon Aromatic Polyketide', Peter J Kramer, Robert J X Zawada, Robert McDaniel, C Richard Hutchinson, David A Hopwood and Chaitan Khosla (1996)

Admin History: Chaitan Khosla is the Wells H. Rauser and Harold M. Petiprin Professor of Chemical Engineering and Chemistry at Stanford University. He took B.Tech in Chemical Engineering, Bombay, 1985; Ph.D. from the California Institute of Technology, 1990 with Jay Bailey working on the expression of the Vitreoscilla Hemoglobin gene. He did his postdoctoral work at the John Innes Centre with David Hopwood. He has been a professor at Stanford since 1992. His research is focused on two realms, the first are to build a molecular understanding of polyketide synthases and the second is focused on the biochemistry of coeliac disease particularly involving tissue transglutaminase.